Publications HAL du labo/EPI 576;1043235 de la collection IBS-FDP

2022

titre
Binding stoichiometry and structural model of the HIV-1 Rev/Importin β complex
auteur
Didier Spittler, Rose-Laure Indorato, Elisabetta Boeri Erba, Elise Delaforge, Luca Signor, Simon Harris, Isabel Garcia-Saez, Andrés Palencia, Frank Gabel, Martin Blackledge, Marjolaine Noirclerc-Savoye, Carlo Petosa
article
Life Science Alliance, 2022, ⟨10.26508/lsa.202201431⟩
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https://hal.archives-ouvertes.fr/hal-03453423/file/2022_LifeSciAlliance_Spittler.pdf BibTex
titre
Convergent vews on disordered protein dynamics from NMR and computational approaches
auteur
Nicola Salvi, Vojtěch Zapletal, Zuzana Jaseňáková, Milan Zachrdla, Petr Padrta, Subhash Narasimhan, Thorsten Marquardsen, Jean-Max Tyburn, Lukáš Žídek, Martin Blackledge, Fabien Ferrage, Pavel Kadeřávek
article
Biophysical Journal, 2022, 121 (20), pp.3785-3794. ⟨10.1016/j.bpj.2022.09.016⟩
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https://hal.archives-ouvertes.fr/hal-03861375/file/Salvi_BJ_text_preaccepted_4FF.pdf BibTex
titre
Intrinsically Disordered Tardigrade Proteins Self‐Assemble into Fibrous Gels in Response to Environmental Stress
auteur
Anas Malki, Jean-Marie Teulon, Aldo Camacho-Zarco, Shu-Wen Chen, Wiktor Adamski, Damien Maurin, Nicola Salvi, Jean-Luc Pellequer, Martin Blackledge
article
Angewandte Chemie International Edition, 2022, 61 (1), pp.e202109961. ⟨10.1002/anie.202109961⟩
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titre
NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins
auteur
Aldo Camacho-Zarco, Vincent Schnapka, Serafima Guseva, Anton Abyzov, Wiktor Adamski, Sigrid Milles, Malene Ringkjøbing Jensen, Lukas Zidek, Nicola Salvi, Martin Blackledge
article
Chemical Reviews, 2022, 122 (10), pp.9331-9356. ⟨10.1021/acs.chemrev.1c01023⟩
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https://hal.archives-ouvertes.fr/hal-03810005/file/Camacho-Zarco%20et%20al.%20Chemical%20reviews.pdf BibTex
titre
Structural dynamics of the C-terminal X domain of Nipah and Hendra viruses controls the attachment to the C-terminal tail of the nucleocapsid protein
auteur
Jean-Marie Bourhis, Filip Yabukarski, Guillaume Communie, Robert Schneider, Valentina Volchkova, Mickaël Frénéat, Francine Gérard, Corinne Ducournau, Caroline Mas, Nicolas Tarbouriech, Malene Ringkjøbing Jensen, Viktor Volchkov, Martin Blackledge, Marc Jamin
article
Journal of Molecular Biology, 2022, 434 (10), pp.167551. ⟨10.1016/j.jmb.2022.167551⟩
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titre
The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a
auteur
Luiza Mamigonian Bessa, Serafima Guseva, Aldo Camacho-Zarco, Nicola Salvi, Damien Maurin, Laura Mariño Perez, Maiia Botova, Anas Malki, Max Nanao, Malene Ringkjøbing Jensen, Rob Ruigrok, Martin Blackledge
article
Science Advances , 2022, 8 (3), pp.eabm4034-1-eabm4034-12. ⟨10.1126/sciadv.abm4034⟩
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https://hal.univ-grenoble-alpes.fr/hal-03621049/file/Sci_Adv_8_eabm4034.pdf BibTex
titre
Visualizing protein breathing motions associated with aromatic ring flipping
auteur
Laura Mariño Pérez, Francesco S Ielasi, Luiza M Bessa, Damien Maurin, Jaka Kragelj, Martin Blackledge, Nicola Salvi, Guillaume Bouvignies, Andrés Palencia, Malene Ringkjøbing Jensen
article
Nature, 2022, ⟨10.1038/s41586-022-04417-6⟩
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https://hal.sorbonne-universite.fr/hal-03582487/file/s41586-022-04417-6.pdf BibTex

2021

titre
$^1$H, $^{13}$C and $^{15}$N Backbone chemical shift assignments of the n-terminal and central intrinsically disordered domains of SARS-CoV-2 nucleoprotein
auteur
Serafima Guseva, Laura Mariño Perez, Aldo Camacho-Zarco, Luiza Mamigonian Bessa, Nicola Salvi, Anas Malki, Damien Maurin, Martin Blackledge
article
Biomolecular NMR Assignments, 2021, pp.1-6. ⟨10.1007/s12104-021-10014-x⟩
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titre
1H, 13C and 15N backbone chemical shift assignments of SARS-CoV-2 nsp3a
auteur
Nicola Salvi, Luiza Mamigonian Bessa, Serafima Guseva, Aldo Camacho-Zarco, Damien Maurin, Laura Marino Perez, Anas Malki, Martin Hengesbach, Sophie Marianne Korn, Andreas Schlundt, Harald Schwalbe, Martin Blackledge
article
Biomolecular NMR Assignments, 2021, 15 (1), pp.173-176. ⟨10.1007/s12104-020-10001-8⟩
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titre
Enthalpy–Entropy Compensation in the Promiscuous Interaction of an Intrinsically Disordered Protein with Homologous Protein Partners
auteur
Jaka Kragelj, Thibault Orand, Elise Delaforge, Laura Tengo, Martin Blackledge, Andrés Palencia, Malene Ringkjøbing Jensen
article
Biomolecules, 2021, 11 (8), pp.1204. ⟨10.3390/biom11081204⟩
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https://hal.univ-grenoble-alpes.fr/hal-03433956/file/Kragelj%20et%20al.%20biomolecules.pdf BibTex
titre
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications
auteur
Nadide Altincekic, Sophie Marianne Korn, Nusrat Shahin Qureshi, Marie Dujardin, Martí Ninot-Pedrosa, Rupert Abele, Marie Jose Abi Saad, Caterina Alfano, Fabio Almeida, Islam Alshamleh, Gisele Cardoso de Amorim, Thomas Anderson, Cristiane Anobom, Chelsea Anorma, Jasleen Kaur Bains, Adriaan Bax, Martin Blackledge, Julius Blechar, Anja Böckmann, Louis Brigandat, Anna Bula, Matthias Bütikofer, Aldo Camacho-Zarco, Teresa Carlomagno, Icaro Putinhon Caruso, Betül Ceylan, Apirat Chaikuad, Feixia Chu, Laura Cole, Marquise Crosby, Vanessa de Jesus, Karthikeyan Dhamotharan, Isabella Felli, Jan Ferner, Yanick Fleischmann, Marie-Laure Fogeron, Nikolaos Fourkiotis, Christin Fuks, Boris Fürtig, Angelo Gallo, Santosh Gande, Juan Atilio Gerez, Dhiman Ghosh, Francisco Gomes-Neto, Oksana Gorbatyuk, Serafima Guseva, Carolin Hacker, Sabine Häfner, Bing Hao, Bruno Hargittay, K. Henzler-Wildman, Jeffrey Hoch, Katharina Hohmann, Marie Hutchison, Kristaps Jaudzems, Katarina Jović, Janina Kaderli, Gints Kalniņš, Iveta Kaņepe, Robert Kirchdoerfer, John Kirkpatrick, Stefan Knapp, Robin Krishnathas, Felicitas Kutz, Susanne Zur Lage, Roderick Lambertz, Andras Lang, Douglas Laurents, Lauriane Lecoq, Verena Linhard, Frank Löhr, Anas Malki, Luiza Mamigonian Bessa, Rachel Martin, Tobias Matzel, Damien Maurin, Seth Mcnutt, Nathane Cunha Mebus-Antunes, Beat Meier, Nathalie Meiser, Miguel Mompeán, Elisa Monaca, Roland Montserret, Laura Mariño Perez, Celine Moser, Claudia Muhle-Goll, Thais Cristtina Neves-Martins, Xiamonin Ni, Brenna Norton-Baker, Roberta Pierattelli, Letizia Pontoriero, Yulia Pustovalova, Oliver Ohlenschläger, Julien Orts, Andrea da Poian, Dennis Pyper, Christian Richter, Roland Riek, Chad Rienstra, Angus Robertson, Anderson Pinheiro, Raffaele Sabbatella, Nicola Salvi, Krishna Saxena, Linda Schulte, Marco Schiavina, Harald Schwalbe, Mara Silber, Marcius da Silva Almeida, Marc Sprague-Piercy, Georgios Spyroulias, Sridhar Sreeramulu, Jan-Niklas Tants, Kaspars Tārs, Felix Torres, Sabrina Töws, Miguel Treviño, Sven Trucks, Aikaterini Tsika, Krisztina Varga, Ying Wang, Marco Weber, Julia Weigand, Christoph Wiedemann, Julia Wirmer-Bartoschek, Maria Alexandra Wirtz Martin, Johannes Zehnder, Martin Hengesbach, Andreas Schlundt, Miguel Á. Treviño
article
Frontiers in Molecular Biosciences, 2021, 8, pp.653148. ⟨10.3389/fmolb.2021.653148⟩
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titre
PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins
auteur
Tamas Lazar, Elizabeth Martínez-Pérez, Federica Quaglia, András Hatos, Lucía Chemes, Javier Iserte, Nicolás Méndez, Nicolás Garrone, Tadeo Saldaño, Julia Marchetti, Ana Julia Velez Rueda, Pau Bernadó, Martin Blackledge, Tiago Cordeiro, Eric Fagerberg, Julie Forman-Kay, Maria Fornasari, Toby Gibson, Gregory-Neal Gomes, Claudiu Gradinaru, Teresa Head-Gordon, Malene Ringkjøbing Jensen, Edward Lemke, Sonia Longhi, Cristina Marino-Buslje, Giovanni Minervini, Tanja Mittag, Alexander Miguel Monzon, Rohit Pappu, Gustavo Parisi, Sylvie Ricard-Blum, Kiersten Ruff, Edoardo Salladini, Marie Skepö, Dmitri Svergun, Sylvain Vallet, Mihaly Varadi, Peter Tompa, Silvio Tosatto, Damiano Piovesan
article
Nucleic Acids Research, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
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https://hal.univ-grenoble-alpes.fr/hal-03433964/file/Lazar%20et%20al.%20NAR.pdf BibTex
titre
Quantitative Description of Intrinsically Disordered Proteins Using Single-Molecule FRET, NMR, and SAXS
auteur
Samuel Naudi-Fabra, Maud Tengo, Malene Ringkjøbing Jensen, Martin Blackledge, Sigrid Milles
article
Journal of the American Chemical Society, 2021, 143 (48), pp.20109-20121. ⟨10.1021/jacs.1c06264⟩
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https://hal.univ-grenoble-alpes.fr/hal-03549077/file/Naudi%20Fabra%20et%20al.%20JACS.pdf BibTex
titre
Sendai Virus and a Unified Model of Mononegavirus RNA Synthesis
auteur
Daniel Kolakofsky, Philippe Le Mercier, Machiko Nishio, Martin Blackledge, Thibaut Crepin, Rob Ruigrok
article
Viruses, 2021, 13 (12), pp.2466. ⟨10.3390/v13122466⟩
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https://hal.univ-grenoble-alpes.fr/hal-03518294/file/Kolakovsky%20et%20al.%20viruses.pdf BibTex
titre
Synergies of Single Molecule Fluorescence and NMR for the Study of Intrinsically Disordered Proteins
auteur
Samuel Naudi-Fabra, Martin Blackledge, Sigrid Milles
article
Biomolecules, 2021, 12 (1), pp.27. ⟨10.3390/biom12010027⟩
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2020

titre
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
auteur
Linda Schulte, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki, Victor-Valentin Hodirnau, Jakob Meier-Credo, Krishna Saxena, Florian Buhr, Julian Langer, Martin Blackledge, Achilleas Frangakis, Clemens Glaubitz, Harald Schwalbe
article
Nature Communications, 2020, 11 (1), pp.5569. ⟨10.1038/s41467-020-19372-x⟩
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titre
Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly
auteur
Serafima Guseva, Sigrid Milles, Malene Ringkjøbing Jensen, Nicola Salvi, Jean-Philippe Kleman, Damien Maurin, Rob W H Ruigrok, Martin Blackledge
article
Science Advances , 2020, 6 (14), pp.eaaz7095. ⟨10.1126/sciadv.aaz7095⟩
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https://hal.univ-grenoble-alpes.fr/hal-02529008/file/Guseva%20et%20al.%20Sci%20Adv.pdf BibTex
titre
Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A
auteur
Aldo Camacho-Zarco, Sissy Kalayil, Damien Maurin, Nicola Salvi, Elise Delaforge, Sigrid Milles, Malene Ringkjøbing Jensen, Darren Hart, Stephen Cusack, Martin Blackledge
article
Nature Communications, 2020, 11 (1), pp.3656. ⟨10.1038/s41467-020-17407-x⟩
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https://hal.univ-grenoble-alpes.fr/hal-02947694/file/Camacho-Zarco%20et%20al.%20Nature%20Com.pdf BibTex
titre
Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage
auteur
Kim Krighaar Rasmussen, Andrés Palencia, Anders Varming, Habiba El-Wali, Elisabetta Boeri Erba, Martin Blackledge, Karin Hammer, Torsten Herrmann, Mogens Kilstrup, Leila Lo Leggio, Malene Ringkjøbing Jensen
article
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (34), pp.20576-20585. ⟨10.1073/pnas.2005218117⟩
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https://hal.univ-grenoble-alpes.fr/hal-02972710/file/Rasmussen%20et%20al.%20PNAS.pdf BibTex
titre
Structural Description of the Nipah Virus Phosphoprotein and Its Interaction with STAT1
auteur
Malene Ringkjøbing Jensen, Filip Yabukarski, Guillaume Communie, Eric Condamine, Caroline Mas, Valentina Volchkova, Nicolas Tarbouriech, Jean-Marie Bourhis, Viktor Volchkov, Martin Blackledge, Marc Jamin
article
Biophysical Journal, 2020, 118 (10), pp.2470-2488. ⟨10.1016/j.bpj.2020.04.010⟩
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https://hal.archives-ouvertes.fr/hal-02867772/file/S0006349520303283.pdf BibTex
titre
Structure, dynamics and phase separation of measles virus RNA replication machinery
auteur
Serafima Guseva, Sigrid Milles, Malene Ringkjøbing Jensen, Guy Schoehn, Rob W H Ruigrok, Martin Blackledge
article
Current Opinion in Virology, 2020, 41, pp.59-67. ⟨10.1016/j.coviro.2020.05.006⟩
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https://hal.univ-grenoble-alpes.fr/hal-03016129/file/Guseva%20et%20al.%20Curr%20Opin%20Virol.pdf BibTex

2019

titre
A Unified Description of Intrinsically Disordered Protein Dynamics under Physiological Conditions Using NMR Spectroscopy
auteur
Wiktor Adamski, Nicola Salvi, Damien Maurin, Justine Magnat, Sigrid Milles, Malene Ringkjøbing Jensen, Anton Abyzov, Christophe J Moreau, Martin Blackledge
article
Journal of the American Chemical Society, 2019, 141 (44), pp.17817-17829. ⟨10.1021/jacs.9b09002⟩
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https://hal.univ-grenoble-alpes.fr/hal-02414561/file/Adamski%20et%20al.%20J%20Am%20Chem%20Soc.pdf BibTex
titre
Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication
auteur
Ambroise Desfosses, Sigrid Milles, Malene Ringkjøbing Jensen, Serafima Guseva, Jacques-Philippe Colletier, Damien Maurin, Guy Schoehn, Irina Gutsche, Rob W H Ruigrok, Martin Blackledge
article
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (10), pp.4256-4264. ⟨10.1073/pnas.1816417116⟩
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https://hal.science/hal-02070475/file/desfosses2019.pdf BibTex
titre
Experimental studies of binding of intrinsically disordered proteins to their partners
auteur
Robert Schneider, Malene Ringkjøbing Jensen, Martin Blackledge
article
Intrinsically Disordered Proteins, Elsevier, pp.139-187, 2019, ⟨10.1016/B978-0-12-816348-1.00005-3⟩
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titre
Intrinsically Disordered Proteins: Dynamics, Binding, and Function
auteur
Nicola Salvi
article
Academic Press. Elsevier, 2019, Dynamics, Binding, and Function, 1st edition, 978-0-12-816348-1
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titre
Mapping Hidden Residual Structure within the Myc bHLH-LZ Domain Using Chemical Denaturant Titration
auteur
Panova Stanislava, Matthew J Cliff, Pavel F Macek, Martin Blackledge, Malene Ringkjøbing Jensen, Nissink Willem M, Kevin J Embrey, Davies Rick, Jonathan P. Waltho
article
Structure, 2019, 27 (10), pp.1537-1546.e4. ⟨10.1016/j.str.2019.07.006⟩
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https://hal.univ-grenoble-alpes.fr/hal-03016176/file/Stanislava%20et%20al.%20Structure.pdf BibTex
titre
Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase
auteur
Vojtěch Kubáň, Pavel Srb, Hana Štégnerová, Petr Padrta, Milan Zachrdla, Zuzana Jaseňáková, Hana Šanderová, Dragana Vítovská, Libor Krasny, Tomáš Koval', Jan Dohnálek, Joanna Ziemska-Legiecka, Marcin Grynberg, Patryk Jarnot, Aleksandra Gruca, Malene Ringkjøbing Jensen, Martin Blackledge, Lukáš Žídek
article
Journal of the American Chemical Society, 2019, 141 (42), pp.16817-16828. ⟨10.1021/jacs.9b07837⟩
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titre
Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database
auteur
Alejandro N Estaña, Nathalie Sibille, Elise Delaforge, Marc Vaisset, Juan Cortés, Pau Bernadó
article
Structure, 2019, 27 (5), pp.381-391.e2. ⟨10.1016/j.str.2018.10.016⟩
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https://hal.laas.fr/hal-01954977/file/Estana_IDPs_Structure_2019.pdf BibTex
titre
Solvent-dependent segmental dynamics in intrinsically disordered proteins
auteur
Nicola Salvi, Anton Abyzov, Martin Blackledge
article
Science Advances , 2019, 5 (6), pp.eaax2348. ⟨10.1126/sciadv.aax2348⟩
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titre
Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences
auteur
Kateřina Melková, Vojtěch Zapletal, Subhash Narasimhan, Séverine Jansen, Jozef Hritz, Rostislav Škrabana, Markus Zweckstetter, Malene Ringkjøbing Jensen, Martin Blackledge, Lukáš Žídek
article
Biomolecules, 2019, 9 (3), pp.105. ⟨10.3390/biom9030105⟩
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titre
The Nucleoprotein and Phosphoprotein of Measles Virus
auteur
Serafima Guseva, Sigrid Milles, Martin Blackledge, Rob W H Ruigrok
article
Frontiers in Microbiology, 2019, 10 (1832), pp.1-10. ⟨10.3389/fmicb.2019.01832⟩
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titre
Vesicular stomatitis virus phosphoprotein dimerization domain is dispensable for virus growth
auteur
Francine Gérard, Marc Jamin, Martin Blackledge, Danielle Blondel, Jean-Marie Bourhis
article
Journal of Virology, 2019, ⟨10.1128/JVI.01789-19⟩
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2018

titre
Characterization of intrinsically disordered proteins and their dynamic complexes: From in vitro to cell-like environments
auteur
Sigrid Milles, Nicola Salvi, Martin Blackledge, Malene Ringkjøbing Jensen
article
Progress in Nuclear Magnetic Resonance Spectroscopy, 2018, 109, pp.79-100. ⟨10.1016/j.pnmrs.2018.07.001⟩
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titre
Characterizing Protein-Protein Interactions Using Solution NMR Spectroscopy.
auteur
Jose Luis Ortega-Roldan, Martin Blackledge, Malene Ringkjøbing Jensen
article
Methods in Molecular Biology, 2018, 1764, pp.73-85. ⟨10.1007/978-1-4939-7759-8_5⟩
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titre
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
auteur
Tanguy Le Marchand, Matteo de Rosa, Nicola Salvi, Benedetta Maria Sala, Loren B Andreas, Emeline Barbet-Massin, Pietro Sormanni, Alberto Barbiroli, Riccardo Porcari, Cristiano Sousa Mota, Daniele de Sanctis, Martin Bolognesi, Lyndon Emsley, Vittorio Bellotti, Martin Blackledge, Carlo Camilloni, Guido Pintacuda, Stefano Ricagno
article
Nature Communications, 2018, 9, pp.1658-1-1658-11. ⟨10.1038/s41467-018-04078-y⟩
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https://hal.archives-ouvertes.fr/hal-01859528/file/Nature_Communications_9_1658.pdf BibTex
titre
Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy
auteur
Elise Delaforge, Jaka Kragelj, Laura Tengo, Andres Palencia, Sigrid Milles, Guillaume Bouvignies, Nicola Salvi, Martin Blackledge, Malene Ringkjøbing Jensen
article
Journal of the American Chemical Society, 2018, 140 (3), pp.1148 - 1158. ⟨10.1021/jacs.7b12407⟩
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titre
Elucidating binding mechanisms and dynamics of intrinsically disordered protein complexes using NMR spectroscopy
auteur
Robert Schneider, Martin Blackledge, Malene Ringkjøbing Jensen
article
Current Opinion in Structural Biology, 2018, 54, pp.10-18. ⟨10.1016/j.sbi.2018.09.007⟩
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titre
Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics
auteur
Kateřina Melková, Vojtěch Zapletal, Séverine Jansen, Erik Nomilner, Milan Zachrdla, Jozef Hritz, Jiří Nováček, Markus Zweckstetter, Malene Ringkjøbing Jensen, Martin Blackledge, Lukáš Žídek
article
Journal of Biological Chemistry, 2018, 293 (34), pp.13297-13309. ⟨10.1074/jbc.RA118.001769⟩
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titre
Probing Protein Dynamics Using Multifield Variable Temperature NMR Relaxation and Molecular Dynamics Simulation
auteur
Baptiste Busi, Jayasubba Reddy Yarava, Albert Hofstetter, Nicola Salvi, Diane Cala-de Paepe, Józef Lewandowski, Martin Blackledge, Lyndon Emsley
article
Journal of Physical Chemistry B, 2018, 122 (42), pp.9697-9702. ⟨10.1021/acs.jpcb.8b08578⟩
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titre
Structural basis of the bacteriophage TP901-1 CI repressor dimerization and interaction with DNA
auteur
Kim Rasmussen, Anders Varming, Simon Schmidt, Kristian Frandsen, Peter Thulstrup, Malene Ringkjøbing Jensen, Leila Lo Leggio
article
FEBS Letters, 2018, 592 (10), pp.1738-1750. ⟨10.1002/1873-3468.13060⟩
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2017

titre
A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.
auteur
Matthew J Whitley, Zhaoyong Xi, Jonathan C Bartko, Malene Ringkjøbing Jensen, Martin Blackledge, Angela M Gronenborn
article
Biophysical Journal, 2017, 112 (6), pp.1135-1146. ⟨10.1016/j.bpj.2017.02.010⟩
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titre
Atomic resolution conformational dynamics of intrinsically disordered proteins from NMR spin relaxation
auteur
Nicola Salvi, Anton Abyzov, Martin Blackledge
article
Progress in Nuclear Magnetic Resonance Spectroscopy, 2017, 102-103, pp.43 - 60. ⟨10.1016/j.pnmrs.2017.06.001⟩
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titre
Dynamic Descriptions of Highly Flexible Molecules from NMR Dipolar Couplings: Physical Basis and Limitations.
auteur
Nicola Salvi, Loïc Salmon, Martin Blackledge
article
Journal of the American Chemical Society, 2017, ⟨10.1021/jacs.7b01566⟩
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titre
Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.
auteur
Danielle C Desravines, Martin Serna Martin, Robert Schneider, Philippe J Mas, Nataliia Aleksandrova, Malene Ringkjøbing Jensen, Martin Blackledge, Darren J Hart
article
Scientific Reports, 2017, 7 (1), pp.3678. ⟨10.1038/s41598-017-03718-5⟩
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2016

titre
Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and Experiment
auteur
Luca Mollica, Luiza M. Bessa, Xavier Hanoulle, Malene Ringkjøbing Jensen, Martin Blackledge, Robert Schneider
article
Frontiers in Molecular Biosciences, 2016, 3 (14), pp.7110 - 7121. ⟨10.3389/fmolb.2016.00052⟩
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titre
Ensemble Structure of the Highly Flexible Complex Formed between Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.
auteur
Filip Yabukarski, Cedric Leyrat, Nicolas Martinez, Guillaume Communie, Ivan Ivanov, Euripedes A Ribeiro, Marlyse Buisson, Francine Gérard, Jean-Marie Bourhis, Malene Ringkjøbing Jensen, Pau Bernadó, Martin Blackledge, Marc Jamin
article
Journal of Molecular Biology, 2016, 428 (13), pp.2671-94. ⟨10.1016/j.jmb.2016.04.010⟩
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titre
Identification of Dynamic Modes in an Intrinsically Disordered Protein Using Temperature-Dependent NMR Relaxation.
auteur
Anton Abyzov, Nicola Salvi, Robert Schneider, Damien Maurin, Rob W H Ruigrok, Malene Ringkjøbing Jensen, Martin Blackledge
article
Journal of the American Chemical Society, 2016, 138 (19), pp.6240-51. ⟨10.1021/jacs.6b02424⟩
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titre
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions
auteur
Elise Delaforge, Sigrid Milles, Jie-Rong Huang, Denis Bouvier, Malene Ringkjøbing Jensen, Michael Sattler, Darren J Hart, Martin Blackledge
article
Frontiers in Molecular Biosciences, 2016, 3, pp.54. ⟨10.3389/fmolb.2016.00054⟩
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titre
Multi-Timescale Dynamics in Intrinsically Disordered Proteins from NMR Relaxation and Molecular Simulation
auteur
Nicola Salvi, Anton Abyzov, Martin Blackledge
article
Journal of Physical Chemistry Letters, 2016, 7 (13), pp.2483 - 2489. ⟨10.1021/acs.jpclett.6b00885⟩
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titre
Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer
auteur
Elias Akoury, Marco D. Mukrasch, Jacek Biernat, Katharina Tepper, Valéry Ozenne, Eckhard Mandelkow, Martin Blackledge, Markus Zweckstetter
article
Protein Science, 2016, ⟨10.1002/pro.2911⟩
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titre
SAXS/SANS on Supercharged Proteins Reveals Residue-Specific Modifications of the Hydration Shell.
auteur
Henry S Kim, Anne Martel, Eric Girard, Martine Moulin, Michael Härtlein, Dominique Madern, Martin Blackledge, Bruno Franzetti, Frank Gabel
article
Biophysical Journal, 2016, 110 (10), pp.2185-94. ⟨10.1016/j.bpj.2016.04.013⟩
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titre
Secondary Structure Prediction of Protein Constructs Using Random Incremental Truncation and Vacuum-Ultraviolet CD Spectroscopy.
auteur
Mária Pukáncsik, Ágnes Orbán, Kinga Nagy, Koichi Matsuo, Kunihiko Gekko, Damien Maurin, Darren J Hart, István Kézsmárki, Beata G Vertessy, Petri Kursula
article
PLoS ONE, 2016, 11 (6), pp.e0156238. ⟨10.1371/journal.pone.0156238⟩
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titre
Self-Assembly of Measles Virus Nucleocapsid-like Particles: Kinetics and RNA Sequence-Dependence.
auteur
Sigrid Milles, Malene Ringkjøbing Jensen, Guillaume Communie, Damien Maurin, Guy Schoehn, Rob W H Ruigrok, Martin Blackledge
article
Angewandte Chemie International Edition, 2016, ⟨10.1002/anie.201602619⟩
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titre
Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1
auteur
Kim Krighaar Rasmussen, Kristian E. H. Frandsen, Elisabetta Boeri Erba, Margit Pedersen, Anders K. Varming, Karin Hammer, Mogens Kilstrup, Peter W. Thulstrup, Martin Blackledge, Malene Ringkjøbing Jensen, Leila Lo Leggio
article
Scientific Reports, 2016, 6, pp.29574. ⟨10.1038/srep29574⟩
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titre
The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex.
auteur
Nicola Salvi, Evangelos Papadopoulos, Martin Blackledge, Gerhard Wagner
article
Angewandte Chemie International Edition, 2016, 55 (25), pp.7176-9. ⟨10.1002/anie.201603254⟩
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2015

titre
Ensemble Calculation for Intrinsically Disordered Proteins Using NMR Parameters.
auteur
Jaka Kragelj, Martin Blackledge, Malene Ringkjøbing Jensen
article
Advances in Experimental Medicine and Biology, 2015, 870, pp.123-47
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titre
Inter-helical conformational preferences of HIV-1 TAR-RNA from maximum occurrence analysis of NMR data and molecular dynamics simulations.
auteur
Witold Andrałojć, Enrico Ravera, Loïc Salmon, Giacomo Parigi, Hashim M Al-Hashimi, Claudio Luchinat
article
Physical Chemistry Chemical Physics, 2015
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titre
Investigating protein conformational energy landscapes and atomic resolution dynamics from NMR dipolar couplings: a review.
auteur
Loïc Salmon, Martin Blackledge
article
Reports on Progress in Physics, 2015, 78 (12), pp.126601
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titre
Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin alpha
auteur
Elise Delaforge, Sigrid Milles, Guillaume Bouvignies, Denis Bouvier, Stephane Boivin, Nicola Salvi, Damien Maurin, Anne Martel, Adam Round, Edward A. Lemke, Malene Ringkjøbing Jensen, Darren J Hart, Martin Blackledge
article
Journal of the American Chemical Society, 2015, 137 (48), pp.15122-15134. ⟨10.1021/jacs.5b07765⟩
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titre
Mapping the conformation of a client protein through the Hsp70 functional cycle.
auteur
Ashok Sekhar, Rina Rosenzweig, Guillaume Bouvignies, Lewis E Kay
article
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (33), pp.10395-400. ⟨10.1073/pnas.1508504112⟩
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titre
Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors.
auteur
Sigrid Milles, Davide Mercadante, Iker Valle Aramburu, Malene Ringkjøbing Jensen, Niccolò Banterle, Christine Koehler, Swati Tyagi, Jane Clarke, Sarah L Shammas, Martin Blackledge, Frauke Gräter, Edward A Lemke
article
Cell, 2015, 163 (3), pp.734-45
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titre
Protein dynamics. Direct observation of hierarchical protein dynamics.
auteur
Józef R Lewandowski, Meghan E Halse, Martin Blackledge, Lyndon Emsley
article
Science, 2015, 348 (6234), pp.578-81
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titre
Structural biology turned on its head.
auteur
Guillaume Bouvignies, Martin Blackledge
article
ChemBioChem, 2015, 16 (7), pp.1033-4. ⟨10.1002/cbic.201500101⟩
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titre
Structural Impact of Tau Phosphorylation at Threonine 231.
auteur
Martin Schwalbe, Harindranath Kadavath, Jacek Biernat, Valéry Ozenne, Martin Blackledge, Eckhard Mandelkow, Markus Zweckstetter
article
Structure (London, England : 1993), 2015, 23 (8), pp.1448-58
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titre
Structure and dynamics of the MKK7-JNK signaling complex.
auteur
Jaka Kragelj, Andrés Palencia, Max H Nanao, Damien Maurin, Guillaume Bouvignies, Martin Blackledge, Malene Ringkjøbing Jensen
article
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (11), pp.3409-14
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titre
The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility
auteur
Rasmus Linser, Nicola Salvi, Rodolfo Briones, Petra Rovó, Bert de Groot, Gerhard Wagner
article
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (40), pp.12390 - 12395. ⟨10.1073/pnas.1513782112⟩
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titre
Visualizing the molecular recognition trajectory of an intrinsically disordered protein using multinuclear relaxation dispersion NMR
auteur
Robert Schneider, Damien Maurin, Guillaume Communie, Jaka Kragelj, D Flemming Hansen, Rob W H Ruigrok, Malene Ringkjøbing Jensen, Martin Blackledge
article
Journal of the American Chemical Society, 2015, 137 (3), pp.1220-9. ⟨10.1021/ja511066q⟩
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2014

titre
Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy.
auteur
Malene Ringkjøbing Jensen, Markus Zweckstetter, Jie-Rong Huang, Martin Blackledge
article
Chemical Reviews, 2014, 114 (13), pp.6632-60
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titre
Exploring the minimally frustrated energy landscape of unfolded ACBP.
auteur
Valéry Ozenne, Jeffrey K Noel, Pétur O Heidarsson, Søren Brander, Flemming M Poulsen, Malene Ringkjøbing Jensen, Birthe B Kragelund, Martin Blackledge, Jens Danielsson
article
Journal of Molecular Biology, 2014, 426 (3), pp.722-34
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titre
Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by (1)H-detected Solid-state NMR.
auteur
Emeline Barbet-Massin, Michele Felletti, Robert Schneider, Stefan Jehle, Guillaume Communie, Nicolas Martinez, Malene Ringkjøbing Jensen, Rob W H Ruigrok, Lyndon Emsley, Anne Lesage, Martin Blackledge, Guido Pintacuda
article
Biophysical Journal, 2014, 107 (4), pp.941-946. ⟨10.1016/j.bpj.2014.05.048⟩
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titre
Intrinsic disorder within the erythrocyte binding-like proteins from Plasmodium falciparum.
auteur
Manuel Blanc, Theresa L Coetzer, Martin Blackledge, Michael Haertlein, Edward P Mitchell, V Trevor Forsyth, Malene Ringkjøbing Jensen
article
BBA - Biochimica et Biophysica Acta, 2014, 1844 (12), pp.2306-2314
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titre
Intrinsically disordered proteins implicated in paramyxoviral replication machinery.
auteur
Guillaume Communie, Rob W H Ruigrok, Malene Ringkjøbing Jensen, Martin Blackledge
article
Current Opinion in Virology, 2014, 5, pp.72-81
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titre
Ligand-dependent dynamics of the active-site lid in bacterial dimethylarginine dimethylaminohydrolase.
auteur
Masooma Rasheed, Christine Richter, Liisa T Chisty, John Kirkpatrick, Martin Blackledge, Martin R Webb, Paul C Driscoll
article
Biochemistry, 2014, 53 (6), pp.1092-104
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titre
Long-range correlated dynamics in intrinsically disordered proteins.
auteur
Giacomo Parigi, Nasrollah Rezaei-Ghaleh, Andrea Giachetti, Stefan Becker, Claudio Fernandez, Martin Blackledge, Christian Griesinger, Markus Zweckstetter, Claudio Luchinat
article
Journal of the American Chemical Society, 2014, 136 (46), pp.16201-9
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titre
Measuring hydrogen exchange rates in invisible protein excited states
auteur
D. Long, Guillaume Bouvignies, L. E. Kay
article
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (24), pp.8820-5. ⟨10.1073/pnas.1405011111⟩
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titre
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins.
auteur
Mihaly Varadi, Simone Kosol, Pierre Lebrun, Erica Valentini, Martin Blackledge, a Keith Dunker, Isabella C Felli, Julie D Forman-Kay, Richard W Kriwacki, Roberta Pierattelli, Joel Sussman, Dmitri I Svergun, Vladimir N Uversky, Michele Vendruscolo, David Wishart, Peter E Wright, Peter Tompa
article
Nucleic Acids Research, 2014, 42 (Database issue), pp.D326-35
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titre
Predictive atomic resolution descriptions of intrinsically disordered hTau40 and α-synuclein in solution from NMR and small angle scattering.
auteur
Martin Schwalbe, Valéry Ozenne, Stefan Bibow, Mariusz Jaremko, Lukasz Jaremko, Michal Gajda, Malene Ringkjøbing Jensen, Jacek Biernat, Stefan Becker, Eckhard Mandelkow, Markus Zweckstetter, Martin Blackledge
article
Structure (London, England : 1993), 2014, 22 (2), pp.238-49
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titre
relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data
auteur
Sébastien Morin, Troels E. Linnet, Mathilde Lescanne, Paul Schanda, Gary S. Thompson, Martin Tollinger, Kaare Teilum, Stephane Gagné, Dominique Marion, Christian Griesinger, Martin Blackledge, Edward J. d'Auvergne
article
Applied Bioinformatics, 2014, 30 (15), pp.2219 - 2220. ⟨10.1093/bioinformatics/btu166⟩
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https://hal.archives-ouvertes.fr/hal-01093687/file/Morin%20et%20al._Bioinformatics_2014.pdf BibTex
titre
Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.
auteur
Yann G J Sterckx, Alexander N Volkov, Wim F Vranken, Jaka Kragelj, Malene Ringkjøbing Jensen, Lieven Buts, Abel Garcia-Pino, Thomas Jové, Laurence van Melderen, Martin Blackledge, Nico a J van Nuland, Remy Loris
article
Structure (London, England : 1993), 2014, 22 (6), pp.854-65
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titre
Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.
auteur
Rasa Sukackaite, Malene Ringkjøbing Jensen, Philippe J Mas, Martin Blackledge, Sara B Buonomo, Darren J Hart
article
Journal of Biological Chemistry, 2014, 289 (20), pp.13903-11
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titre
Structure of Nipah virus unassembled nucleoprotein in complex with its viral chaperone.
auteur
Filip Yabukarski, Philip Lawrence, Nicolas Tarbouriech, Jean-Marie Bourhis, Elise Delaforge, Malene Ringkjøbing Jensen, Rob W H Ruigrok, Martin Blackledge, Viktor Volchkov, Marc Jamin
article
Nature Structural and Molecular Biology, 2014, pp.754-9
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titre
Targeting the disordered C terminus of PTP1B with an allosteric inhibitor.
auteur
Navasona Krishnan, Dorothy Koveal, Daniel H Miller, Bin Xue, Sai Dipikaa Akshinthala, Jaka Kragelj, Malene Ringkjøbing Jensen, Carla-Maria Gauss, Rebecca Page, Martin Blackledge, Senthil K Muthuswamy, Wolfgang Peti, Nicholas K Tonks
article
Nature Chemical Biology, 2014, 10 (7), pp.558-66
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titre
Testing the validity of ensemble descriptions of intrinsically disordered proteins.
auteur
Malene Ringkjøbing Jensen, Martin Blackledge
article
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (16), pp.E1557-8
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titre
Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
auteur
Jie-Rong Huang, Lisa R Warner, Carolina Sanchez, Frank Gabel, Tobias Madl, Cameron D Mackereth, Michael Sattler, Martin Blackledge
article
Journal of the American Chemical Society, 2014, 136 (19), pp.7068-76
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